Symposium / Mini Symposium
Please see here for Workshop, Poster Session, Luncheon Seminar & 1st Workshop of Gender Equality Program

(List of Theme)

May 28 (Mon)

Symposium (8:45-11:45)	S1	Cell signaling underlying the regulation of cell motility and the cytoskeleton
	S4	Protein aggregation and proteolysis
	S9	Mutagenesis projects
Mini Symposium (16:15-18:45)	MS2A	Crosstalk between cell-cell and cell-matrix adhesion
	MS3A	Molecular mechanisms of nuclear organization and dynamics
	MS6	Organelle transport, partition, and inheritance
	MS8	Gene regulatory networks for shaping organisms
Workshop (16:15-18:45)	W4 W9	Theme 4 [Life of proteins] Workshop Theme 9 [Technical advances] Workshop
	W5A	Theme 5 [Cell proliferation/Differentiation/Apoptosis/Stem cells/Signal transduction] Workshop 1
	W7A	Theme 7 [Regeneration/Morphogenesis/Organogenesis] Workshop 1
	W7B	Theme 7 [Regeneration/Morphogenesis/Organogenesis] Workshop 2

May 29 (Tue)

Symposium (8:45-11:45)	S3	Chromatin dynamics for the replication, repair and segregation of chromosomes
	S6	Organelle assembly and dysfunction
	S7	Signaling networks that regulate morphogenesis and organogenesis
Mini Symposium (16:15-18:45)	MS2B	Regulation of cell fate and tissue development by the extracellular matrix
	MS4B	Functionalization and quality control of proteins: surveillance and handling systems
	MS5	The roles of fluctuations, oscillations and waves in biological phenomena
	MS7B	New horizon of Wnt signaling
	MS9A	Technical applications for bioimaging: from single molecules to whole organsisms
	MS9B	Frontiers in RNA biology
Workshop (16:15-18:45)	W1	Theme 1 [Cytoskeleton/Cell motility/Cell migration] Workshop
	W3	Theme 3 [Chromosome/Cell nucleus/Gene expression] Workshop

May 30 (Wed)

Symposium (8:30-11:30)	S2	Cell polarity and tissue morphogenesis
	S5	Molecular basis for stem cell regulation
	S8	Frontiers in molecular, evolutional and comparative biology
Mini Symposium (15:15-17:45)	MS1	Control of cell shape and motility: new approaches to understand its mechanistic basis
	MS3B	Signaling via phosphoinositide 3-kinases
	MS4A	Autophagy
	MS7A	Molecular basis controlling the development and regeneration
Workshop (15:15-17:45)	W2	Theme 2 [Cell adhesion/ECM/Cell-cell interaction] Workshop
	W5B	Theme 5 [Cell proliferation/Differentiation/Apoptosis/Stem cells/Signal transduction] Workshop 2
	W6	Theme 6 [Intracellular trafficking/Organelles] Workshop
	W8	Theme 8 [Evolution/Phylogeny/Comparative embryology] Workshop

(List of Schedule) (List of Program Committee)

(List of Program Committee)

S1
Cell signaling underlying the regulation of cell motility and the cytoskeleton
May 28 (Mon) 8:45-11:45 Room A (3F Main Hall)

Organizers	:	Masaki Inagaki (Aichi Cancer Ctr.) Kozo Kaibuchi (Nagoya Univ.)
S1-1		Essential role of phosphatidylinositol-3, 4, 5-triphosphate in the control of spindle orientation parallel to the cell-substrate adhesion plane ○Fumiko Toyoshima1, 2, Shigeru Matsumura1, Hiroko Morimoto1, Eisuke Nishida1 1Department of Cell and Developmental Biology, Graduate School of Biostudies, 2PRESTO, JST
S1-2		Organizing Microtubules in Dorsal Closure Ferenc Jankovics2, Aynur Kaya1, Jerome Solon1, ○Damian Brunner1 1Cell Biology and Biophysics Unit, European Molecular Biology Laboratory, Meyerhofstrasse1, 69117 Heidelberg, Germany, 2Biological Research Center, Institute of Genetics, H-6701 Szeged, POB 521, Temesvari krt. 62., Hungary
S1-3		Roles of Rho family GTPases and Par complex in directional migration ○Kozo Kaibuchi Nagoya University Graduate School of Medicine, Department of Cell Pharmacology
S1-4		A keratin filament-binding protein Albatross: an unexpected regulator of apical junctional complex ○Akihito Inoko1, Masaki Inagaki1, 2 1Division of Biochemistry, Aichi Cancer Center Research Institute, 2Department of Cellular Oncology, Nagoya University Graduate School of Medicine
S1-5		Intermediate filaments as signaling organizers ○John E. Eriksson Dept. of Biology, Abo Akademi University and Turku Centre for Biotechnology, University of Turku and Abo Akademi University
S1-6		Functional analysis of keratins in mouse development using large-scale genome engineering ○Thomas M. Magin1, Preethi Vijayaraj1, Cornelia Kroeger1, Elke Winterhager2 1Univ. Bonn, Inst. of Physiol. Chemistry, Div. of Cell Biochemistry, 2University of Essen, Dept. of Anatomy

MS1
Control of cell shape and motility: new approaches to understand its mechanistic basis
May 30 (Wed) 15:15-17:45 Room D (4F 409+410)

Organizers	:	Asako Sugimoto (RIKEN) Shiro Suetsugu (Univ. of Tokyo)
MS1-1		Mycoplasma gliding -a novel mechanism of cell motility ○Makoto Miyata1,2 1Department of Biology, Graduate School of Science, Osaka City University, Osaka 558-8585, 2PRESTO JST
MS1-2		GUIDANCE MECHANISMS FOR INVASIVE MIGRATION OF A CELL CLUSTER ○Pernille Rorth European Molecular Biology Laboratory (EMBL)*
MS1-3		A new approach to the mechanism of cell elongation and cellular membrane remodeling using Drosophila spermatids. ○Tatsuhiko Noguchi, Michiko Koizumi, Shigeo Hayashi Laboratory for Morphogenetic Signaling Center for Developmental Biology, RIKEN Kobe 2-2-3 Minatojima-minamimachi Chuo-ku, Kobe 650-0047, JAPAN
MS1-4		Establishment of cell polarity in C. elegans embryos Fumio Motegi, ○Asako Sugimoto Developmental Genomics, RIKEN CDB, Kobe 650-0047
MS1-5		Integration of mechanical and chemical signals in cell protrusion ○Gaudenz Danuser The Scripps Research Institute
MS1-6		Single-molecule imaging analysis of stochastic signal transduction in chemotactic response of eukaryotic cells ○Masahiro Ueda Laboratories for Nanobiology, Graduate School of Frontier Biosciences, Osaka University, Osaka 565-0871
MS1-7		Connecting the membrane to the actin cytoskeleton by the BAR, EFC, and RCB domain proteins and WASP/WAVE proteins. ○Shiro Suetsugu1, 2, 3, Tadaomi Takenawa3, 4 1Institute of Molecular and Cellular Biosciences, The University of Tokyo, 2, JST, 3Dept. Biochemistry, Institute of Medical Sciences, University of Tokyo, 4Kobe University School of Medicine

(List of Program Committee)

S2
Cell polarity and tissue morphogenesis
May 30 (Wed) 8:30-11:30 Room I (5F International Conference Room 501)

Organizer	:	Shigeo Ohno (Yokohama City Univ.)
S2-1		A novel signaling pathway by which PAR-aPKC system regulates cell-substrate interaction ○Atsushi Suzuki, Kazunari Yamashita, Yoshiko Amano, Shigeo Ohno Yokohama City University, Graduate School of Medical Science, Yokohama 236-0004
S2-2		Vesicle transport-dependent Rap1 activation and its implication in axon formation ○Toshiaki Sakisaka, Yoshimi Takai Dept. Mol. Biol. and Biochem., Osaka Univ. Grad. Sch. Med.
S2-3		Roles of cadherin-catenin adhesion complex in epithelial morphogenesis ○Akira Nagafuchi, Satoshi Komiya, Yoshitaka Fukunaga, Edgardo Abelardo Division of Cellular Interactions, IMEG, Kumamoto University, Kumamoto 860-0811
S2-4		Early cell polarity and neural progenitor cell fate in a vertebrate nervous system. ○Faculty of Life Sciences, University of Manchester, UK The University of Manchester
S2-5		Regulation of cell surface mechanics underlying tissue morphogenesis ○Thomas Lecuit Institute of Developmental Biology of Marseille-Luminy, France.

MS2A
Crosstalk between cell-cell and cell-matrix adhesion
May 28 (Mon) 16:15-18:45 Room E (4F 413+414)

Organizers	:	Tatsushi Igaki (Yale Univ. Sch. of Med.) Hisakazu Ougita (Osaka Univ.)
MS2A-1		Crosstalk between nectin and integrin in the formation of cell-cell junctions ○Hisakazu Ogita, Yoshimi Takai Graduate School of Medicine, Department of Molecular Biology and Biochemistry, Osaka University 565-0871
MS2A-2		Crosstalk mechanisms between repulsive guidance receptors plexins and cell adhesion receptor integrins ○Izumi Oinuma, Hironori Katoh, Manabu Negishi Labolatory of Molecular Neurobiology, Graduate School of Biostudies, Kyoto University, Kyoto 606-8501
MS2A-3		Requirement of ZO-1 for the formation of belt-like adherens junction and tight junction during epithelial cell polarization ○Junichi Ikenouchi1, Kazuaki Umeda2, Sachiko Tsukita3, 5, Mikio Furuse4, Shoichiro Tsukita1, 5 1Department of Cell Biology, Faculty of Medicine, Kyoto University, 2Department of Molecular Pharmacology,Graduate School of Medical Sciences, Kumamoto University, 3Organismal Biosystems Laboratory, Graduate School of Frontier Biosciences, Osaka University, 4Division of Cellular and Molecular Medicine, Kobe University Graduate School of Medicine, 5Solution Oriented Research for Science and Technology, Japan Science and Technology Corporation
MS2A-4		Planar Cell Polarity (PCP) genes regulate exclusion of motor neurons from the neuroepithelial layer in the developing zebrafish hindbrain ○Hironori Wada1, Hideomi Tanaka1, 2, Satomi Nakayama1, Miki Iwasaki1, 2, Hitoshi Okamoto1, 2 11Lab for Developmental Gene Regulation, BSI, RIKEN, 22CREST, JST
MS2A-5		Molecular link between loss of cell polarity and tumor malignancy ○Tatsushi Igaki, Tian Xu Yale University School of Medicine, Department of Genetics
MS2A-6		Molecular mechanisms of invadopodium formation and its role in cancer invasion and metastasis ○Hideki Yamaguchi, Kiyoko Fukami Laboratory of Genome and Biosignal, School of Life Sciences, Tokyo University of Pharmacy and Life Sciences, Tokyo 192-0392

MS2B
Regulation of cell fate and tissue development by the extracellular matrix
May 29 (Tue) 16:15-18:45 Room E (4F 413+414)

Organizers	:	Eri Arikawa-Hirasawa (Juntendo Univ.) Ryo Iwamoto (Osaka Univ.)
		Introduction
MS2B-1		Diverse roles of the heparan sulfate proteoglycan perlecan in organ development and homeostasis ○Eri Arikawa-Hirasawa Juntendo University School of Medicine, Research Institute for Diseases of Old Age
MS2B-2		Perlecan modulates FGF and VEGF signaling and is essential for vascular invasion in the development of the cartilage growth plate ○Muneaki Ishijima1,2, Eri Arikawa-Hirasawa3, Kentaro Hozumi1, Nobuharu Suzuki1, Keisuke Kosaki1, Yoshihiko Yamada1 1Laboratory of Cell and Developmental Biology, NIDCR, NIH, 2Department of Orthopaedics, Juntendo University School of Medicine, 3Research Institute for Diseases of Old Age, Juntendo University School of Medicine
MS2B-3		Cloning and functional analysis of Pikachurin: a novel Agrin/Perlecan-related protein localized at the active zone of retinal photoreceptor ribbon synapse Shigeru Sato1,2, Akiko Tani1, ○Takahisa Furukawa1 1Department of Developmental Biology, Osaka Bioscience Institute, 2School of Medicine, Department of Visual Science, University of Osaka
MS2B-4		Regulation of morphogenesis by heparan sulfate modifying enzymes, SulfFPs. ○Kensuke Shiomi, Satoshi Nagamine, Takuya Okada, Kazuko Keino-Masu, Masayuki Masu Department of Molecular Neurobiology, Graduate School of Comprehensive Human Sciences, University of Tsukuba
MS2B-5		Regulation of HB-EGF function by HSPGs ○Ryo Iwamoto, Eisuke Mekada Research Institute for Microbial Diseases, Osaka University, Osaka 565-0871
MS2B-6		MIG-17, an ADAMTS protease, regulates organ morphogenesis in C. elegans Yukihiko Kubota, Kiyotaka Ohkura, Kayo Nagata, ○Kiyoji Nishiwaki RIKEN Center for Developmental Biology
MS2B-7		Effect of cell surface proteolysis by membrane type-1 MMP (MT1-MMP) on malignant progression of tumors ○Naohiko Koshikawa, Motoharu Seiki Division of Cancer Cell research, Institute of Medical Science, University of Tokyo 108-8639
MS2B-8		Dental cell differentiation regulated by laminin ○Satoshi Fukumoto Faculty of Dental Science, Section of Pediatric Dentistry, Kyushu University, Fukuoka 812-8582
		Conclusion

(List of Program Committee)

S3
Chromatin dynamics for the replication, repair and segregation of chromosomes
May 29 (Tue) 8:45-11:45 Room I (5F International Conference Room 501)

Organizer	:	Yoshinori Watanabe (Univ. of Tokyo)
S3-1		Chromatin Dynamics in DNA damage response ○Tsuyoshi Ikura Department of Biochemistry, Tohoku University Graduate School of Medicine
S3-2		Shaping the chromosome: architecture and regulation of condensins ○Tatsuya Hirano1, 2, Itay Onn2, Nobuki Aono1, 2, Michiko Hirano2, Takao Ono1 1RIKEN Discovery Research Institute, Wako, Saitama 351-0198, 2Spring Harbor Laboratory, Cold Spring Harbor NY11724, USA
S3-3		Mitotic chromosome condensation and segregation ○Frank Uhlmann Chromosome Segregation Laboratory, Cancer Research UK London Research Institute, London, WC2A 3PX, UK
S3-4		Analyses of Eukaryotic Chromosome Structure and Function by Array Based Genomic Approach ○Katsuhiko Shirahige Center for Biological Resources and Informatics, Tokyo Institute of Technology , kanagawa 226-8501
S3-5		Centromeric protection by shugoshin in mammalian oocytes and somatic cells ○Yoshinori Watanabe Institute of Molecular Cellular Biosciences, University of Tokyo, Tokyo 113-0032
S3-6		Universal centromere/kinetochore mechanism ○Mitsuhiro Yanagida Kyoto University, Graduate School of Biostudies

MS3A
Molecular mechanisms of nuclear organization and dynamics
May 28 (Mon) 16:15-18:45 Room I (5F International Conference Room 501)

Organizers	:	Hiroshi Kimura (Kyoto Univ.) Masahiko Harata (Tohoku Univ.)
		Opening remarks Hiroshi Kimura Kyoto Univ.
MS3A-1		Actin-related proteins involved in chromatin and nuclear organization Takahito Yoshida1, Kenji Shimada2, Kazuto Kugo3, Kunihiro Ohta3, Susan Gasser2, ○Masahiko Harata1 1Graduate School of Agricultural Science, Tohoku University, Sendai 981-8555, 2Friedrich Miescher Institute, Base Switzerland, 3RIKEN, Wako 351-0198
MS3A-2		Spatial organization of gene expression ○Wouter de Laat Dept. Of Cell Biology, Erasmus MC,PO Box 2040, 3000 CA Rotterdam, The Netherlands
MS3A-3		Dynamic Assembly and Inactivation of Human Centromere on Satellite DNA ○Hiroshi Masumoto1, Teruaki Okada1, Yasuhide Okamoto1, Megumi Nakano2, Jun-ichirou Ohzeki2, Vladimir Larionov2 1Division of Biological Science, Graduate School of Science, Nagoya University, 2Lab. of Biosystems and Cancer, National Cancer Institute, National Institutes of Health
MS3A-4		Nuclear architecture and SUMO modification ○Noriko Saitoh1, Yuko Nakatsu1, Yuko Hino1, Yasuhiro Uchimura2, Hisato Saitoh2, Mitsuyoshi Nakao1 1Dept of Regen. Med, IMEG, Kumamoto Univ, Kumamoto 860-0811, 2Dept. of Biol. Sci, Kumamoto Univ, Kumamoto 860-8555
MS3A-5		Compartmentalisation of androgen receptor protein-protein interactions in living cells* Martin E. van Royen1, Sonia M. Cunha1, Maartje C. Brink2, Karin A. Mattern1, Hendrikus J. Dubbink1, Pernette J. Verschure2, Jan Trapman1, ○Adriaan B. Houtsmuller1 1Department of Pathology; Josephine Nefkens Institute; Erasmus MC Rotterdam; The Netherlands; a.houtsmuller@erasmusmc.nl, 2Swammerdam Institute for Life Sciences; University of Amsterdam; The Netherlands.
MS3A-6		Mitosis-coupled positioning of centrosomes in C. elegans embryo ○Akatsuki Kimura1, 2 1Cell Architecture Laboratory, Center for Frontier Research, National Institute of Genetics, Mishima 411-8540, 2Department of Genetics, SOKENDAI, Mishima 411-8540

MS3B
Signaling via phosphoinositide 3-kinases
May 30 (Wed) 15:15-17:45 Room E (4F 413+414)

Organizer	:	Takehiko Sasaki (Akita Univ.)
MS3B-1		Roles of 3-phosphorylated phosphoinositides ○Takehiko Sasaki1, Shunsuke Takasuga1, Junko Sasaki1, Akira Suzuki2 1Dept. Pathol. and Immunol., Akita Univ., 2Dept. Mol. Med., Akita Univ.
MS3B-2		Use of phosphoinositide-binding domains for the quantification and visualization of D3-phosphoinositides in cancer cells ○Toshiki Itoh, Tsukasa Oikawa, Kazuya Tsujita, Tadaomi Takenawa Division of Biochemistry, Institute of Medical Science, University of Tokyo
MS3B-3		Role of PDK1 in Glucose Metabolism ○Wataru Ogawa, Hiroshi Inoue, Yasuo Okamoto, Hiroshi Sakaue, Kyoko Nakamura, Kensuke Furukawa, Yoshiaki Kido, Masato Kasuga Div. Diabetes, Metabolism, Endocrinology, Kobe Univ.
MS3B-4		PTEN: its deregulation and tumorigensis ○Tomohiko Maehama Department of Biochemistry and Cell Biology, National Institute of Infectious Diseases
MS3B-5		Regulation of stem cell systems by PI3K-Akt signal ○Tohru Kimura1, Akira Suzuki3, Toru Nakano1, 2 1Graduate School of Medicine, Department of Pathology, Osaka University, Osaka 565-0871, 2Graduate School of Frontier Biosciences, Osaka University, Osaka 565-0871, 3Department of Molecular Biology, Akita University School of Medicine, Akita 010-8543

(List of Program Committee)

S4
Protein aggregation and proteolysis
May 28 (Mon) 8:45-11:45 Room I (5F International Conference Room 501)

Organizers	:	Teru Ogura (Kumamoto Univ.) Kenji Yamamoto (Kyushu Univ.)
S4-1		The physical basis of strain diversity in the yeast prion [PSI+] system ○Motomasa Tanaka1, 2 1RIKEN BSI, 2JST PRESTO
S4-2		Sensing Stress: Misfolded Proteins in Aging and Neurodegenerative Disease ○Richard I. Morimoto, Anat Ben-Zvi, Susan Fox, Susana Garcia, Tali Gidalevitz, Catarina Lima, Patrick McMullen, Cindy Voisine, Daniel Czyz, Kai Orton, James West Department of Biochemistry, Molecular Biology and Cell Biology, Rice Institute for Biomedical Research, Northwestern University, Evanston, Il. 60208 USA
S4-3		Role of cytosolic chaperonin CCT in preventing the cytotoxicity of aggregation prone proteins ○Hiroshi Kubota, Akira Kitamura, Shoshiro Hirayama, Kazuhiro Nagata Department of Molecular and Cellular Biology, Institute for Frontier Medical Sciences, Kyoto University, Kyoto 606-8397, Japan.
S4-4		Mechanism of protein disaggregation by AAA chaperones Tobias Haslberger, Peter Tessarz, Axel Mogk, ○Bernd Bukau ZMBH, University of Heidelberg
S4-5		Molecular basis for the diversity of mammalian proteasomes ○Shigeo Murata Laboratory of Frontier Science, Tokyo Metropolitan Institute of Medical Science
S4-6		Observation of Ectodomain Shedding of Membrane-anchored Growth factors in Living cells ○Atsuko Sehara Institute for Frontier Medical Sciences

MS4A
Autophagy
May 30 (Wed) 15:15-17:45 Room F (4F 411+412)

Organizers	:	Noboru Mizushima (Tokyo Med. & Dent. Univ.) Tamotsu Yoshimori (Osaka Univ.)
		Introduction Tamotsu Yoshimori Osaka Univ.
MS4A-1		Hierarchy of Atg proteins in pre-autophagosomal structure organization ○Kuninori Suzuki1, 2, Yuka Kubota1, Takayuki Sekito1, Yoshinori Ohsumi1, 2 1National Institute for Basic Biology, Department of Cell Biology, Okazaki 444-8585, 2School of Life Science, Department of Basic Biology, The Graduate University for Advanced Studies
MS4A-2		Molecular Mechanism of LC3 Lipidation and the Role of LC3 in Autophagosome Formation ○Naonobu Fujita, Takeshi Noda, Tamotsu Yoshimori Department of Cellular Regulation, Research Institute for Microbial Diseases, Osaka University, 3-1 Yamadaoka, Suita, Osaka, 565-0871
MS4A-3		Methanol-induced autophagy: a novel autophagic pathway found in the methylotrophic yeast Pichia pastoris Shun-ichi Yamashita, Hiroya Yurimoto, ○Yasuyoshi Sakai Division of Applied Life Sciences, Graduate School of Agriculture, Kyoto University
MS4A-4		Degradation of peroxisomes in mammalian cells ○Sayuri Kuge1, Yukio Fujiki1, 2 1Department of Biology, Faculty of Science, Kyushu University Graduate School, Fukuoka 812-8581, 2JST, CREST
MS4A-5		Autophagy is essential for development of fertilized eggs Mirei Murakami1, Akiko Kuma1, 2, Akitsugu Yamamoto3, Satoshi Tsukamoto1, ○Noboru Mizushima1, 2 1Department of Physiology and Cell Biology, Tokyo Medical and Dental University, Tokyo 113-8519, 2SORST, Japan Science and Technology Agency, Kawaguchi 332-0012, 3Department of Bio-Science, Nagahama Institute of Bio-Science and Technology, Nagahama 526-0829
MS4A-6		Autophagic defense system in innate immunity ○Ichiro Nakagawa Division of Bacteriology, Department of Infectious Disease Control, International Research Center for Infectious Diseases, The University of Tokyo, Institute of Medical Science
MS4A-7		Selective Autophagy Regulates Formation of Intracytoplamic Inclusions ○Masaaki Komatsu1, 2, 3, Eiki Kominami1, Keiji Tanaka2 1Department of Biochemistry, Juntendo University School of Medicine, Tokyo 113-8421, 2Laboratory of Frontier Science, Tokyo Metropolitane Institute of Medical Science, Tokyo 113-8613, 3PRESTO, JST, Kawaguchi 332-0012

MS4B
Functionalization and quality control of proteins: surveillance and handling systems
May 29 (Tue) 16:15-18:45 Room F (4F 411+412)

Organizers	:	Kenji Kohno (Nara Inst. of Sci. & Technol.) Hideki Taguchi (Univ. of Tokyo)
MS4B-1		Structural basis for protein disulfide bond formation in the cell ○Kenji Inaba1, Koreaki Ito2 1Medical Institute of Bioregulation, Kyushu University, 812-8582, 2Institute for Virus Research, Kyoto University, 606-8507
MS4B-2		Role of Chaperonin in the cell: Filamentous morphology in GroE-depleted Escherichia coli is induced by impaired folding of FtsE ○Hideki Taguchi Department of Medical Genome Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa 277-8562
MS4B-3		How does SecA ATPase drive protein translocation? ○Hiroyuki Mori1, 2, Koreaki Ito1, 2, 3 1Inst. Virus Res., Kyoto Univ., 2CREST, JST, 3Inst. Protein Res., Osaka Univ.
MS4B-4		Protein function studied by fluorescence correlation spectroscopy ○Masataka Kinjo Laboratory of Supramolecular Biophysics, RIES, Hokkaido University, Sapporo, Japan
MS4B-5		Multiple endoplasmic reticulum stress-sensing units that synergistically regulate Ire1. ○Yukio Kimata, Kenji Kohno Graduate School of Biological Sciences, Nara Institute of Science and Technology, Nara 630-0192
MS4B-6		Flexibility of translocon and driving force for polypeptide chain translocation ○Masao Sakaguchi, Yuichiro Kida Graduate School of Lifescience

(List of Program Committee)

S5
Molecular basis for stem cell regulation
May 30 (Wed) 8:30-11:30 Room A (3F Main Hall)

Organizers	:	Shinya Yamanaka (Kyoto Univ.) Tetsuya Taga (Kumamoto Univ.)
S5-1		Molecular mechanisms to restrict differentiation ability of stem cells ○Hitoshi Niwa Laboratory for Pluripotent cell studies, RIKEN Center for Developmental Biology (CDB), Kobe 650-0047
S5-2		Generation of high quality iPS cells Kazutoshi Takahashi1, Keisuke Okita1, Masato Nakagawa1, Takashi Aoi1, Tomoko Ichisaka1, 2, ○Shinya Yamanaka1, 2 1Department of Stem Cell Biology, Institute for Frontier Medical Sciences, Kyoto University, Kyoto 606-8507, 2CREST, Japan Science and Technology Agency, Saitama 332-0012
S5-3		Human Embryonic Stem Cells: Self Renewal and Directed Differentiation ○Hongkui Deng Department of Cell Biology and Genetics, College of Life Sciences, Peking University
S5-4		Culture and genetic modification of male germline stem cells ○Takashi Shinohara Dept of Molecular Genetics, Graduate School of Medicine, Kyoto University
S5-5		Assembly of an RNP Complex for Intracellular mRNA Transport and Translational Control ○Anne Ephrussi European Molecular Biology Laboratory, Meyerhofstrasse 1, 69117 Heidelberg, Germany
S5-6		Molecular basis for cell-fate determination in the developing mouse brain Shinji Fukuda, Takeshi Shimizu, Toshihiro Inoue, Tetsushi Kagawa, ○Tetsuya Taga Department of Cell Fate Modulation, Institute of Molecular Embryology and Genetics, Kumamoto University, Kumamoto, 860-0811, Japan

MS5
The roles of fluctuations, oscillations and waves in biological phenomena
May 29 (Tue) 16:15-18:45 Room D (4F 409+410)

Organizers	:	Ryoichiro Kageyama (Kyoto Univ.) Hiroki R. Ueda (RIKEN)
MS5-1		A generic mechanism for adaptive growth rate regulation ○Chikara Furusawa1, 3, Kunihiko Kaneko2, 3 1Graduate School of Information Science, Osaka University, 2Department of Pure and Applied Sciences, University of Tokyo, 3Complex Systems Biology Project, ERATO, JST
MS5-2		Order and function of noisy morphological dynamics in a single Dictyostelium discoideum cell ○Yusuke T. Maeda1, Junya Inose1, Miki Matsuo1, 2, Suguru Iwaya1, Masaki Sano1 1Graduate School of Science, Department of Physics, the University of Tokyo, Tokyo 113-0033, 2Aihara Complexity Modelling Project, ERATO, JST, Tokyo 151-0064
MS5-3		Desynchronization of multi-cellular clocks underlies the population-level singularity behavior of mammalian circadian clock. ○Hideki Ukai1, Tetsuya J. Kobayashi1, 2, Hiroki R. Ueda1 1Laboratory for Systems Biology,Center for Developmental Biology, Riken, Kobe 650-0047, 2Research Fellow of Japan Society of the Promotion Science, Kobe 650-0047
MS5-4		New molecular mechanism regulating Hes7 oscillation in the somite segmentation clock ○Yasutaka Niwa1, 2, Yoshito Masamizu1, 2, Tianxiao Liu1, Rika Nakayama3, Chu-Xia Deng4, Ryoichiro Kageyama1, 2 1Institute for Virus Research, Growth Regulation, University of Kyoto, 2Japan Science and Technology Agency, CREST, 3Center for Developmental Biology, RIKEN Kobe, 4Genetics of Development and Disease Branch, National Institute of Health
MS5-5		Self-organizing Mechanism for Development of Space-filling Dendrites ○Kaoru Sugimura1, 2, Tadashi Uemura1, Atsushi Mochizuki3 1Graduate School of Biostudies, Kyoto University, 2RIKEN BSI, 3NIBB

(List of Program Committee)

S6
Organelle assembly and dysfunction
May 29 (Tue) 8:45-11:45 Room F (4F 411+412)

Organizers	:	Katsuyoshi Mihara (Kyushu Univ.) Hisao Kondoh (Kyushu Univ. / Mitsubishi Kagaku Inst. of Life Sci.)
S6-1		Peroxisome Biogenesis: Membrane Assembly, Matrix Protein Import, Morphogenesis, and Peroxisome Assembly Disorders ○Yukio Fujiki1, 2 1Department of Biology, Faculty of Sciences, Kyushu University Graduate School, Fukuoka 812-8581, 2JST, CREST, Kawaguchi, 332-0012, Japan
S6-2		Protein Import into Peroxisomes Harald W. Platta, Fouzi El Magraoui, Silke Grunau, Astrid Korneli, Wolfgang Girzalsky, ○Ralf Erdmann Ruhr Universitat Bochum, Institut fur Physiologische Chemie D-44780 Bochum, Germany
S6-3		Complex pathyways and machineries for mitochondrial protein import ○Toshiya Endo Deaprtment of Chemistry, Graduate School of Science, Nagoya University
S6-4		Mitochondrial Fusion Protects Against Neurodegeneration in the Cerebellum Hsiuchen Chen, Scott A. Detmer, ○David C. Chan Division of Biology, California Institute of Technology, 1200 East California Blvd, MC114-96, Pasadena, CA 91125
S6-5		p97ATPase-mediated biogenesis of the Golgi and ER ○Hisao Kondo1, 2, Go Totsukawa2, Yayoi Kaneko2, Yoko Ogawa2 1Department of Molecular Biology, Kyushu University, Fukuoka 812-8582, 2Mitsubishi Kagaku Institute of Life Science, Tokyo 194-8511
S6-6		Membrane Dynamics during Autophagy in Yeast ○Yoshinori Ohsumi National Institute for Basic Biology, Department of Cell Biology

MS6
Organelle transport, partition, and inheritance
May 28 (Mon) 16:15-18:45 Room D (4F 409+410)

Organizers	:	Mitsunori Fukuda (Tohoku Univ. / RIKEN) Shinya Miyagishima (RIKEN)
MS6-1		Origin and Evolution of the Chloroplast Division Machinery ○Shin-ya Miyagishima Initiative Res. Program, FRS, RIKEN
MS6-2		The cyclin-dependent kinase, Cdk1, directly regulates vacuole inheritance via phosphorylation of the vacuole-specific myosin V receptor Yutian Peng, ○Lois Weisman Life Sciences Institute and Department of Cell and Developmental Biology, University of Michigan, Ann Arbor, MI 48109
MS6-3		Regulation of mitochondrial morphology and dynamics by the F-box protein Mfb1 Noriko Okamoto1, Janet Shaw1, ○Koji Okamoto1, 2 1Department of Biochemistry, University of Utah School of Medicine, Salt Lake City, UT 84112-5650, USA, 2Division of Molecular Cell Biology, National Institute for Basic Biology, Okazaki 444-8585, Japan
MS6-4		Selective intracellular transports in Drosophila ○Satoshi Goto1, Masato Abe1, Tsubasa Tanaka2, Youka Tominaga1, Akira Nakamura2 1MITILS, 2CDB, RIKEN
MS6-5		Shisa controls setting-up of the signaling receptors in the endoplasmic reticulum ○Akihito Yamamoto RIKEN Center for Developmental Biology, laboratory for Vertebrate Body Plan
MS6-6		Small GTPase Rab27 and its effectors regulate trafficking of secretory granules ○Mitsunori Fukuda1, 2 1Department of Developmental Biology and Neurosciences, Graduate School of Life Sciences, Tohoku University, Miyagi 980-8578, 2Fukuda Initiative Res. Unit, RIKEN, Saitama 351-0198

(List of Program Committee)

S7
Signaling networks that regulate morphogenesis and organogenesis
May 29 (Tue) 8:45-11:45 Room A (3F Main Hall)

Organizers	:	Hisato Kondo (Osaka Univ.) Yoshiko Takahashi (Nara Inst. of Sci. & Technol.)
S7-1		A cross talk between germ cells and somatic cells during sex differentiation of the gonad Chikako MORINAGA2, Hiromi KUROKAWA1, Daisuke SAITO1, Shuhei NAKAMURA1, Takashi SASAKI3, Shuichi ASAKAWA3, Nobuyoshi SHIMIZU3, Hiroshi MITANI4, Makoto FURUTANI-SEIKI2, Hisato KONDOH5, ○Minoru TANAKA1 1Lab. of Mol. Genet. for Reproduction, NIBB, Okazaki 444-0874, 2Kondoh Research Team, Kyoto 606-8305, 3Keio Univ. School of Medicine, Tokyo 160-8582, 4Grad. Sch. of Frontier Science, Univ. of Tokyo , Chiba 277-8562, 5Grad. Sch. of Frontier Biosciences, Osaka Univ. Osaka 565-0871
S7-2		How to leave the brain: exit strategies of the optic vesicle and beyond Juan-Ramon Martinez-Morales1, Martina Rembold1, Felix Loosli1, Richard J. Adams2, ○Joachim Wittbrodt1 1Developmental Biology Unit, EMBL, Meyerhofstrasse 1, 69117 Heidelberg, Germany, 2Department of Physiology, Development and Neuroscience, University of Cambridge, Downing Street, Cambridge CB2 3DY, UK
S7-3		Determinative roles of FGF and Wnt signals in dorsal iris-derived lens regeneration in newt eye Toshinori Hayashi1, 3, Nobuhiko Mizuno1, 4, Ritsuko Takada2, Shinji Takada2, ○Hisato Kondoh1 1Graduate School of Frontier Biosciences, Osaka University, 2Okazaki Institute for Integrative Biosciences, National Institutes of Natural Sciences, 3Virginia Merril Bloedel Hearing Research Center, University of Washington School of Medicine, 4Department of Life Sciences, Graduate School of Arts and Sciences, The University of Tokyo
S7-4		Gene Regulatory Networks During Myogenesis: Understanding the Logic ○Eileen Furlong EMBL, Heidelberg, Germany
S7-5		Notch-Delta signaling in lens induction and functional genomics in Xenopus ○Hajime Ogino, Robert M. Grainger Department of Biology, University of Virginia, Charlottesville, VA22904, U.S.A
S7-6		Somitic contribution to the formation of dorsal aorta involves cell migration regulated by Notch and ephrin ○Yoshiko Takahashi1, 2, Emi Ohata1, 2, Tadayoshi Watanabe1, Teruaki Takahashi1, Koichi Kawakami3, Jun Kohyama1, 4, Hideyuki Okano4, Yuki Sato1, 2 1Nara Institute of Science and Technology, Nara, 2CDB, RIKEN, Kobe, 3NIG, Mishima, 4Keio Univ. Med. School, Tokyo
S7-7		Signalling in mammalian regeneration ○Nadia Rosenthal Mouse Biology Unit, EMBL-Monterotondo Outstation, via Ramarini 32, 00016, Monterotondo-Scalo (Rome), Italy

MS7A
Molecular basis controlling the development and regeneration
May 30 (Wed) 15:15-17:45 Room I (5F International Conference Room 501)

Organizers	:	Koji Tamura (Tohoku Univ.) Kimiko Fukuda (Tokyo Metrop. Univ.)
MS7A-1		Molecular basis of anterior-posterior patterning during planarian regeneration ○Yoshihiko Umesono1, Kazu Itomi2, Yumi Saito1, Yoshimichi Tabata3, Fyan Son3, Nobuko Suzuki3, Ryoko Araki3, Masumi Abe3, kiyokazu Agata1 1Department of Biophysics, Graduate School of Science, Kyoto University, 2RIKEN CDB, 3Transcriptome Research Center, National Institute of radiological Sciences
MS7A-2		Regeneration of fish fin ○Yuki Nakatani, Masanobu Nishidate, Misato Fujita, Atsushi Kawakami, Akira Kudo Department of Biological Information, Tokyo Institute of Technology, Yokohama 226-8501
MS7A-3		New Aspects of development and maintenance of taste bud cells ○Tadashi Okubo1, 2, Larysa Pevny3, Brigid Hogan2 1Okazaki Institute for Integrative Bioscience, National Institutes of Natural Sciences, Okazaki,444-8787 JAPAN, 2Department of Cell Biology, Duke University Medical Center, NC 27710 USA, 3Department of Genetics, University of North Carolina at Chapel-Hill, NC 27599 USA
MS7A-4		Step-wise changes in chromosome architecture regulate Shh expression in the mouse limb bud ○Takanori Amano, Toshihiko Shiroishi Mammalian Genetics Laboratory, Genetic Strains Research Center, National Institute of Genetics. Mishima, Shizuoka 411-0845
MS7A-5		RhoA and Microtubule Dynamics Control Cell-Basement membrane Interaction in EMT during Gastrulation ○Yukiko Nakaya, Erike Sukowati, Guojun Sheng Center for Developmental Biology, RIKEN
MS7A-6		Visualization of cell death signal during rotation of the Drosophila male terminali ○Erina Kuranaga, Masayuki Miura Department of Genetics, Graduate School of Pharmaceutical Sciences, University of Tokyo

MS7B
New horizon of Wnt signaling
May 29 (Tue) 16:15-18:45 Room I (5F International Conference Room 501)

Organizer	:	Kunimasa Ohta (Kumamoto Univ.) Shinichi Nakagawa (RIKEN)
MS7B-1		Dissection of Wnt Signaling Pathways by Genome-wide RNAi Kerstin Bartscherer, Nadege Pelte, Dierk Ingelfinger, ○Michael Boutros German Cancer Research Center
MS7B-2		Wnt protein requires an unexpected type of lipid modification for its secretion. ○Shinji Takada Okazaki Institute for Integrative Biosciences, National Institutes of Natural Sciences
MS7B-3		c-hairy1 controls retinal stem cell maintenance downstream of Wnt signaling, independently of Notch singnaling at the ciliary marginal zone. ○Fumi Kubo1, 2, Masatoshi Takeichi2, 3, Shinichi Nakagawa1 1Frontier Research System, RIKEN, 2Graduate school of Biostudies, Kyoto University, 3Center for Developmental Biology, RIKEN
MS7B-4		Tsukushi controls proliferation of retinal stem cells by Wnt signaling inhibition ○Kunimasa Ohta1, 2 1Graduate School of medical Sciences, Department of Developmental Neurobiology, Kumamoto University, Kumamoto 860-8556, 2PRESTO, JST, Saitama 332-0012
MS7B-5		NMDA-Receptor activation induces calpain-Mediated β-catenin cleavages for triggering gene expression. ○Kentaro Abe1, 2, Masatoshi Takeichi1, 2 1RIKEN Center for Developmental Biology, 2-2-3 Minatojima-Minamimachi, Chuo-ku, Kobe 650-0047, 2Graduate School of Biostudies, Kyoto University, Kitashirakawa, Sakyo-ku, Kyoto 606-8502
MS7B-6		Brain wiring: what can we learn from Wnt signalling? ○Patricia C. Salinas Department of Anatomy and Developmental Biology, University College London. London WC1 6BT. UK.

(List of Program Committee)

S8
Frontiers in molecular, evolutional and comparative biology
May 30 (Wed) 8:30-11:30 Room F (4F 411+412)

Organizers	:	Gen Yamada (Kumamoto Univ.) Yuji Yokouchi (Kumamoto Univ.) Yoh Iwasa (Kyushu Univ.)
		Opening comment Gen Yamada Kumamoto Univ.
S8-1		Conserved non-coding sequences derived from SINEs ○Norihiro Okada Tokyo Institute of Technology
S8-2		Evolutionary studies of the Central Nervous System and Brain by Comparative Gene Expressionics ○Takashi Gojobori Center for Information Biology and DNA Data Bank of Japan, National Institute of Genetics, Mishima, Japan
S8-3		Developmental bases for early evolution of vertebrates ○Shigeru Kuratani Laboratory for Evolutionary Morphology, Center for Developmental Biology, RIKEN
S8-4		Sex, deleterious mutations and the evolution of non-random essential gene distributions ○Michael Knop EMBL, Meyerhofstr. 1, D-69117 Heidelberg, Germany
S8-5		Genome-wide Comparison of Developmental Genes in Plants: difference from the evolution of animal developmental genes ○Mitsuyasu Hasebe1, 2, 3 1National Institute for Basic Biology, 2Graduate School of Advanced Studies, 3ERATO JST
		Closing comment Gen Yamada Kumamoto Univ.

MS8
Gene regulatory networks for shaping organisms
May 28 (Mon) 16:15-18:45 Room F (4F 411+412)

Organizers	:	Sumihare Noji (Univ. of Tokushima) Yutaka Satou (Kyoto Univ.)
		Opening remarks Noriyuki Satoh Kyoto Univ.
MS8-1		Towards Computer Modeling of Common Architectures behind Transcriptional Regulatory Regions ○Kenta Nakai1, Takehiro Kusakabe2 1Institute of Medical Science, University of Tokyo, Tokyo 108-8639, 2Department of Life Science, Graduate School of Life Science, University of Hyogo, Hyogo 678-1297
MS8-2		Control of developmental timing by microRNAs and their targets in C. elegans ○Ryusuke Niwa, Frank J. Slack Department of Molecular, Cellular and Developmental Biology, Yale University, USA
MS8-3		Gene regulatory network for sea urchin endomesoderm specification ○Paola Oliveri, Qiang Tu, Roger Revilla, Eric Davidson Caltech Biology 156-29, Pasadena, CA, 91125, USA
MS8-4		Transcriptional control networks in the Ciona embryo ○Yutaka Satou Graduate School of Science, Kyoto University
MS8-5		Gene regulatory networks for anterior-posterior patterning in a phylogenetically basal insect Gryllus bimaculatus, as revealed by RNAi ○Taro Mito, Hideyo Ohuchi, Sumihare Noji Department of Life Systems, The University of Tokushima, Tokushima 770-8506
MS8-6		Dissecting the regulatory logic underlying the architecture of the Hoxd gene cluster ○Francois Spitz1, Denis Duboule2 1EMBL Developmental Biology Unit, Heidelberg Germany, 2NCCR "Frontiers in Genetics", University of Geneva and Ecole Polytechnique Federale de Lausanne, Switzerland
		Closing Sumihare Noji Univ. of Tokushima

(List of Program Committee)

S9
Mutagenesis projects
May 28 (Mon) 8:45-11:45 Room F (4F 411+412)

Organizers	:	Masatake Araki (Kumamoto Univ.) Makoto Furutani-Seiki (Kumamoto Univ.)
Chairperson	:	Kenji Imai (Tokai Univ.)
S9-1		Functional genomics in post-genome era: comprihensive mutagenesis in model vertebrates ○Kenji Imai Department of Molecular Life Science, Division of Basic Medical Science and Molecular Medicine, Tokai University School of Medicine, Kanagawa 259-1193
S9-2		Medaka and zebrafish complement in uncovering vertebrate genome functions ○Makoto Furutani-Seiki Division of Bioinformatics, Institute of Resource Development and Analysis (IRDA), Faculty of Medical and Pharmaceutical Sciences, Kumamoto University.
S9-3		Maternal control of vertebrate development: adult mutant screens from the zebrafish Florence Marlow, Elliott Abrams, Tripti Gupta, Lee Kapp, Wenyan Mei, Beth Holloway, ○Mary Mullins University of Pennsylvania School of Medicine, Department of Cell and Developmental Biology, 1211 BRB II, Philadelphia, PA19104-6058 USA
S9-4		News from the Munich ENU Mutagenesis Project: and insights into bone and cartilage related phenotypes ○Martin Hrabe de Angelis GSF National Research Center for Environment and Health, Institut for Experimental Genetics, Neuherberg, Germany
S9-5		The European Conditional Mouse Mutagenesis Program(EUCOMM) ○Wolfgang Wurst GSF National Research Center for Environment and Health, Institute of Developmental Genetics, Munich, Germany

MS9A
Technical applications for bioimaging: from single molecules to whole organisms
May 29 (Tue) 16:15-18:45 Room B (4F 401+402+403)

Organizer	:	Takeharu Nagai (Hokkaido Univ.)
MS9A-1		Perspectives on bioimaging technologies ○Takeharu Nagai Research Institute for Electronic Science, Hokkaido University, Sapporo 060-0812
MS9A-2		Design, synthesis and biological application of fluorescent probes, which convert biological signals to chemical output ○Kazuya Kikuchi Graduate School of Engineering, Osaka University, Osaka 565-0871
MS9A-3		Single molecule measurements of Linear and Rotational Bio-motor ○Akihiko Ishijima, Yuichi Inoue, Hajime Fukuoka Institute of Multidisciplinary, Research for Advanced Materials, Tohoku University, Sendai 980-8577
MS9A-4		Live imaging analysis of caspase activation in Drosophila programmed cell death in vivo ○Kiwamu Takemoto1, 2, Erina Kuranaga1, Ayako Tonoki1, Masayuki Miura1 1Dept. Genetics, Grad. Sch. Pharma. Sci., Univ. Tokyo, 2Lab.NanoSystem Physiology, Res.Inst.Elect.Sci., Hakkaido Univ.
MS9A-5		in vivo functional imaging of neuroral and secreatory activities by using two-photon microscopy ○Tomomi Nemoto Center for brain experiment, National Institute for Physiological Sciences, Okazaki 444-8585
MS9A-6		Biomolecular imaging in living subjects using split-reporter reconstitution methods ○Takeaki Ozawa Institute for Molecular Science
MS9A-7		Visualizing molecules in living mammalian animals using Degraton probes ○Yoshihiro Miwa1, 2, Naoki Yoshida1, Junko Tanaka1 1Graduate School of Comprehensive Human Sciences, Department of Molecular Pharmacology, University of Tsukuba, Tsukuba, 305-8575, 2PRESTO, JST

MS9B
Frontiers in RNA biology
May 29 (Tue) 16:15-18:45 Room C (4F 404+405+406)

Organizer	:	Tokio Tani (Kumamoto Univ.)
MS9B-1		microRNA functions ○Stephen Cohen European Molecular Biology Laboratory
MS9B-2		Differential regulation of germline mRNAs in soma and germ cells by zebrafish miR-430 ○Kunio Inoue Department of Biology, Faculty of Science, Kobe University, Kobe 657-8501
MS9B-3		Mass spectrometric characterization of small non-coding RNAs ○Tsutomu Suzuki Graduate School of Engineering, Department of Chemistry and Biotechnology, University of Tokyo, Tokyo 113-8656
MS9B-4		Functional RNomics of C. elegans ○Chisato Ushida1, 2, 3, Takahiro Ogasawara1, Jun-ichi Amakawa1, Yuko Endo1, Yuki Sugawara1, Akira Muto1, 3, Yusuke Hokii2 1Department of Biochemistry and Biotechnology, Faculty of Agriculture and Life Science, Hirosaki University, 3 Bunkyo-cho, Hirosaki, Aomori 036-8561, 2The United Graduate School of Agricultural Sciences, Iwate University, 3RNA Research Center, Hirosaki University
MS9B-5		Visual screening revealed novel localized RNAs in yeast ○Tomoko Andoh, Yukiko Oshiro, Sachiko Hayashi, Hideki Takeo, Sayaka Ohba, Tokio Tani Graduate School of Science and Technology, Department of Biological Sciences, Kumamoto University, Kumamoto 860-8555
MS9B-6		The dynamics of pre-mRNAs at speckles in living cells revealed by iFRAP studies ○Yo Ishihama1, Hisashi Tadakuma2, Tokio Tani3, Takashi Funatsu1 1Graduate School of Pharmaceutical Sciences, The University of Tokyo, 2Department of Applied Physics, The University of Tokyo, 3Department of Biological Sciences, Graduate School of Science and Technology, Kumamoto University
MS9B-7		A transgenic reporter system reveals expression profiles and regulation mechanisms of alternative splicing in vivo ○Hidehito Kuroyanagi1, 2, Masatoshi Hagiwara1,2 1School of Biomedical Science, Tokyo Medical and Dental University, Tokyo 113-8510, 2Medical Research Institute, Tokyo Medical and Dental University, Tokyo 113-8510

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